Alnylam Pharmaceuticals


ABOUT ALNYLAM
Our Science Is Changing the Way Medicine Treats DiseaseTM
Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020, and AMVUTTRA® (vutrisiran) in 2022. We are advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.
What’s in a Name?
AL-NY-LAM. Our name may not be the easiest to pronounce, but once you learn it, you’ll never forget it. Alnylam is derived from “Alnilam,” the bright center star in the constellation Orion’s belt, which has been used by navigators for thousands of years and symbolizes our passion for discovery.
RNAi Therapeutics—An Innovative New Class of Medicines
Medicines based on RNAi work by “silencing” or disabling the production (“expression”) of the genes that cause specific diseases. In doing so, RNAi therapeutics work “upstream” of most other classes of medicines, such as small molecules and monoclonal antibodies, by targeting the “root” genetic cause of a disease rather than its symptoms. To learn more about our science, click here.
RNAi is the core discovery that forms the therapies Alnylam is developing. It is recognized as a major scientific breakthrough—but how does it work, exactly?
Vision, Mission, and Values
Our Vision - Harnessing a revolution in biology for human health®.
Our Mission - Build a top-tier, global, independent biopharmaceutical company founded on RNAi.
Our Core Values - Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
CAREERS AT ALNYLAM
Join Our Team and Grow With Us
At Alnylam, we are driven by our mission to translate the Nobel Prize-winning discovery of RNA interference (RNAi) into an innovative, new class of medicines. We’re motivated in this endeavor by the bravery and perseverance of people with unmet medical needs who live with rare and genetic diseases. They are the focus of our efforts, and we exist as a company because of them. That knowledge and commitment to patients is present in everything we do, every day.
At The Forefront of What’s Next
For Patients
Our goal, which is well underway, is to become a world-class biopharmaceutical company that can independently develop and deliver innovative medicines based on RNAi to patients worldwide. We have a deep pipeline of early to late stage investigational therapies, and 2018 marked the approval of our first medicine—the world’s first RNAi therapeutic. Even though we’ve been around since 2002, we’re just getting started!
For Employees
We are growing quickly and hiring across North America, Europe, Asia, and Latin America for a wide variety of roles. We’re seeking smart, passionate, “change the world” kind of people who are ready to say, “challenge accepted.” Our 1,500 (and counting!) employees are building a diverse, equitable, inclusive, and high-performing global organization that celebrates team achievement and recognizes individual contributions.
We’re at the forefront of what’s next for patients, and perhaps your career also.
Search among Alnylam Pharmaceuticals jobs
Jobs: 1 - 10 of 69 |

Cambridge, Massachusetts
This role is considered Virtual. Overview We are seeking a highly skilled and experienced Principal Solution Architect to join our HR Technology team. As a key member of our department, you will be responsible for overseeing the design, imp...
12h
Job Type | Full Time |

Cambridge, Massachusetts
Overview Alnylam Pharmaceuticals is seeking an imaginative clinical scientist drug developer for the role of Senior Clinical Scientist. This is an opportunity to assume a foundational and strategic role in building Alnylam's rapidly expandi...
12h
Job Type | Full Time |

Cambridge, Massachusetts
Overview The Research department at Alnylam has an exciting opportunity available for a highly motivated research scientist to join our Next Wave biology group. Our mission is to identify new therapeutic siRNA targets across various tissue ...
12h
Job Type | Full Time |

Senior Manager, Training & Knowledge Management - Clinical Development
Cambridge, Massachusetts
This role is considered Hybrid. Overview Reporting to the Head of Standards, Process & Training - Clinical Development, the Sr. Manager - Training & Knowledge Management serves as a GCP area training and knowledge management Subject Matter ...
12h
Job Type | Full Time |

Business Account Executive, TTR - Syracuse
Cambridge, Massachusetts
This role is considered Virtual. Overview We are looking for experienced Business Account Executives (BAEs) with specialty sales experience to promote AMVUTTRA. hATTR-PN and ATTR-CM patients often spend years undiagnosed and misdiagnosed. T...
12h
Job Type | Full Time |

Cambridge, Massachusetts
This role is considered Hybrid. Responsibilities: The Director, Feasibility Center of Excellence (CoE) is responsible for leading predictable and competitive delivery of indication, program, study, country, and site feasibility across the C...
1d
Job Type | Full Time |

Executive Director, Program Lead
Cambridge, Massachusetts
This role is considered Hybrid. Development Program Lead The Development Program Leader will be a strategic leader responsible for building an integrated development strategy that is intimately linked to the global commercialization strateg...
2d
Job Type | Full Time |

Cambridge, Massachusetts
This role is considered Hybrid. Overview We are seeking an experienced and strategic Tax Director to lead all aspects of tax compliance, planning, and reporting for our dynamic biotech organization. This role is critical in ensuring global ...
2d
Job Type | Full Time |

Senior Manager, Patient Marketing
Cambridge, Massachusetts
This role is considered Hybrid. Overview The Senior Manager, Community & Patient Programs will lead strategic initiatives designed to enhance patient engagement, elevate community presence, and drive brand impact through meaningful patient-...
3d
Job Type | Full Time |

Business Account Executive, TTR - Dallas East
Cambridge, Massachusetts
This role is considered Virtual. Overview We are looking for experienced Business Account Executives (BAEs) with specialty sales experience to promote AMVUTTRA. hATTR - PN and ATTR -CM patients often spend years undiagnosed and misdiagnosed...
3d
Job Type | Full Time |