Executive Director, Transformation & Integration Lead

Jazz Pharmaceuticals is undertaking a bold, enterprise-wide transformation to reimagine our operating model and build a patient-centric, agile, and scalable rare disease organization delivering differentiated, precise customer experiences.

This Executive Director, Transformation & Integration Lead is a senior, enterprise leader responsible for setting direction and driving execution of one or more mission-critical transformation programs that shape the future of Jazz. This role operates as a trusted advisor and strategic partner to senior leaders with accountability for designing, orchestrating, and embedding large-scale change across functions.

This is a high-visibility, high-impact role for a leader who operates comfortably at the most senior levels of the organization, influences without authority, and balances strategic vision with hands-on execution. The Transformation Lead will lead integrations for new acquisitions and other business development activities. They will also own complex, multi-year initiatives, navigate ambiguity, and challenge the status quo to deliver measurable, sustainable outcomes.

Key Responsibilities

Enterprise Transformation Strategy & Vision

• Translate Jazz's enterprise transformation vision into integrated, multi-year strategies, roadmaps, and value cases across assigned functional or enterprise domains

• Partner with fellow Transformation Leads, and senior leaders across Jazz to identify, prioritize, and shape transformation initiatives that drive a high performing organization, growth, patient impact and cost efficiency

• Define future-state operating models considering portfolio evolution, market dynamics, digital enablement, and organizational capabilities

End-to-End Integration and Transformation Leadership

• Serve as accountable executive owner for integrations and key transformation programs, with responsibility for outcomes from concept through full-scale implementation and sustainment

• Lead complex integrations and initiatives spanning multiple workstreams, functions, and geographies, ensuring alignment to enterprise objectives and interdependencies

• Oversee design and implementation of new ways of working, including structure, governance, decision rights, processes, incentives, capabilities, and technology

Executive Partnership & Influence

• Act as a thought partner and challenger to senior leaders, providing objective insight, rigorous analytics, and scenario-based recommendations

• Engage in productive challenge with EC members and functional leaders to drive alignment, resolve trade-offs, and accelerate decision-making

• Represent integration and transformation progress, risks, and outcomes to the Executive Committee and other senior governance forums

Change Leadership & Organizational Adoption

• Set the change agenda and ensure deep, lasting embedding of integration and transformation outcomes across Jazz

• Lead enterprise-wide change management strategies, including stakeholder engagement, communications, capability building, and cultural reinforcement

• Anticipate and actively manage resistance, enabling leaders and teams to adopt new mindsets and behaviors aligned with a customer- and patient-first orientation

Cross-Functional & Matrix Leadership

• Lead and develop matrixed integration andtransformation teams and workstream leaders, fostering accountability, collaboration, and high performance

• Partner closely with executive leaders of assigned functions (e.g., R&D, Commercial, G&A, Digital) to ensure seamless integration and execution of transformation initiatives

• Model enterprise thinking and drive solutions that optimize outcomes for Jazz as a whole, not individual functions

Performance Management & Value Delivery

• Define enterprise-level KPIs, success metrics, and value realization plans linked to integration andtransformation objectives

• Monitor progress rigorously, course correct as needed and ensure delivery of committed outcomes

• Provide transparent, executive-level reporting on milestones, risks, and impact

Qualifications

• Bachelor's degree required; advanced degree (MBA, PhD, or equivalent) preferred

• 12+ years of progressive leadership experience in life sciences, healthcare, management consulting, or enterprise transformation roles, working in a team environment

• Proven record of leading integrations in a global pharmaceutical or biotech organizations for both assets in development and commercialized assets

• Experience driving large-scale, complex, cross-functional transformations with measurable business impact; ability to lead cross functional teams

• Demonstrated ability to operate credibly at the Executive Committee level, including preparing and delivering executive-level presentations

• Deep expertise in one or more areas such as Commercial, R&D, G&A, digital transformation, operating model design, or enterprise change

• Strong systems thinker with the ability to connect strategy, data, operating models, and culture

• Highly effective influencer who works across silos and leads through ambiguity without direct authority

• Exceptional analytical, strategic, and problem-solving capabilities.

• Experience with agile, design thinking, lean, or modern change methodologies strongly preferred

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