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Medical Affairs Medical Director- Pain

Vertex Pharmaceuticals Incorporated
paid time off, 401(k)
United States, Massachusetts, Boston
50 Northern Avenue (Show on map)
Oct 02, 2025

Job Description

General Summary:

The Medical Director, Medical Affairs Strategy will provide medical leadership for the US Pain team and will be responsible for developing the medical strategy and medical plan as well as executing against the medical plan for US Pain. This role will lead a team that will collaborate closely with cross-functional groups to ensure that scientific and medical strategies are aligned with broader corporate and key stakeholder needs as well as ensuring the voice of the patient and medical community is integrated into product strategies.

Key Duties and Responsibilities:

  • Develops medical affairs plans, including Launch and Life Cycle Management study plans
  • Critically interprets scientific data, determines the potential impact of new research on clinical practice, and uses scientific and clinical data to formulate frameworks and disease management approaches
  • Provides input from medical community into clinical development and commercial strategies
  • Effectively communicates scientific data through presentations and publications
  • Ensures country/regional insights and needs are considered in global medical strategies and activities
  • Provides scientific input and expertise as a medical reviewer and supports the development of global medical, commercial, regulatory, and reimbursement documents
  • Performs/oversees medical/scientific training for Medical, Commercial, and other internal stakeholders
  • Reviews investigator-sponsored study (ISS) proposals and other research grants
  • Supports projects as assigned by the Sr Med Dir including supporting Medical Symposiums, Webinars, Videos, Medical Education Content development and Training, and Medical Society relationships
  • Leads Medical Advisory Boards
  • Supports Commercial Speaker Training
  • Supports the development of the Integrated Evidence Generation Plan
  • As a people manager within the organization, may have financial accountabilities and human resource responsibilities for assigned staff

Knowledge and Skills:

  • Deep understanding of US medical, regulatory and commercial (including payer) environments
  • Excellent understanding of government and industry guidelines, regulations, laws, etc., for appropriate scientific/medical exchange and communication with key external stakeholders (e.g., healthcare providers, payers, advocacy bodies)
  • Deep understanding of market access in the US
  • Excellent written and oral communication skills to influence others internally/externally
  • Critical ability to develop relationships in a highly matrixed environment, as well as external relationships with global, regional and local thought leaders and industry experts
  • Ability to engage in positive dialogue and resolve conflicts in a constructive manner
  • High fluency/digital literacy in use of PowerPoint

Education and Experience:

  • M.D. degree or equivalent (e.g., D.O.)
  • Typically requires a minimum of 5 years post US/UK/Canada residency/fellowship academic clinical experience.
  • Typically requires at least 3-5 years of industry experience working in the biotech/pharma/implantable medical device industry or the equivalent combination of education and experience
  • Typically requires experience in a Medical Affairs function and in the analysis of research (clinical) data and publications; working knowledge of biostatistics as well as scientific and clinical research methods, and clinical study design
  • Orthopedic or Surgical sub-specialty highly desirable.

Pay Range:

$236,800 - $355,200

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

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