Senior Program Manager

1. Human Research Operations & Team Leadership

• Direct protocol development, regulatory compliance, study activation, and study executionacross the Division Chief's research portfolio.
• Lead Study Management System Oversight, ensuring effective use of platforms such as OnCore or REDCap:

  Protocol & Study Setup- Oversee the accurate documentation and activation of protocols and amendments.

  Participant Management- Oversight of enrollment, consent, and visit scheduling.

  Data Capture & Quality Control- Ensure timely and accurate data entry, integration with EHR/EDC systems.

  Regulatory & Compliance Monitoring- Track IRB approvals, safety reporting, and maintain GCP-compliant audit trails.

  Financial & Resource Tracking- Oversee study budgets, billing compliance, and resource allocation.

  Reporting & Analytics- Generate real-time dashboards and reports for investigators and leadership.

• Develop and enforceStandard Operating Procedures (SOPs)for research operations.
• Providetraining and mentorshipto research staff to ensure high-quality, compliant study execution.
• Oversee recruitment, onboarding, and professional development of research assistants and junior staff; serve as their administrative supervisor under a matrix reporting model.
• Foster a positive, inclusive, and compliant workplace culture aligned with MGB and departmental values.

2. Grant Administration & Program Finances

• Managepre- and post-award activitiesfor the Division Chief's research portfolio, in close collaboration with hospital and departmental research management teams.
• Serve aspoint person for grant submissionsto MGB, NIH, and other funders; refine the submission pipeline by building efficient processes and templates.
• Prepare, monitor, and updatebudgets, forecasts, and spending reportsfor multiple funded projects.
• Coordinate with central teams oncontracting, cost transfers, salary allocations, and grant closeouts.
• Ensurefinancial compliancewith NIH, federal, sponsor, and institutional guidelines.
• Provide leadership withfinancial dashboards and projectionsto guide decision-making and ensure appropriate use of project resources according to project goals, timelines, and milestones.
• Review costs and leadcost-reduction effortsto ensure financial sustainability and compliance.

3. Strategic Infrastructure Development

• Developonboarding curricula and training workflowsto standardize research staff preparation across the lab and division.
• Design and implementresearch management systems, workflows, and templatesthat improve operational efficiency, compliance, and reporting(e.g., protocol activation workflows, IRB submission checklists, REDCap dashboards, budget development worksheets, and standardized PI/funder report templates).
• Createinfrastructure that can be shared across the division, supporting other PIs and their teams through scalable tools.

4. Communications & Visibility

• Oversee the development ofinternal and external communications(including newsletters, reports, social media, and outreach materials)with execution support from administrative staff and MGB communications/development offices.
• Promote the visibility of the division, locally and globally, among academic and commercial partners, funding agencies, philanthropic supporters, and the broader public.
• Coordinate withMGB communications and development officesto align messaging and maximize impact.

Required

• Degree in life sciences, public health, healthcare administration, or related field
• 5+ years of progressive experience inhuman research operations(clinical trials, regulatory compliance, research administration).
• Demonstrated ability to overseeprotocol compliance, IRB processes, and Good Clinical Practice (GCP)standards.
• Experience withstudy management systems(OnCore, REDCap, or equivalent).
• Experience withpre- and post-award financial administration(e.g., grants administration, budget preparation, effort reporting, financial oversight and compliance).
• Strong leadership, organizational, and communication skills, with the ability to manage complex projects and mentor staff.

Preferred

• Project Management Professional (PMP)or equivalent certification.
• Experience working inacademic medical centersor large research organizations
• Familiarity with Mass General Brigham systems and NIH funding mechanisms.
• Certified Research Administrator (CRA)or equivalent credential.

Why Join Us?

• Opportunity to serve as theprimary operational leaderfor a large and innovative research team with direct capacity to shape the mission.
• Buildinfrastructure and systemsthat will have an impact across the entire division.
• Collaborate withworld-class faculty and researchersat Mass General Brigham.
• Enjoy stronginstitutional support, including dedicated pre- and post-award research management teams.
• This position requiresonsite presence at Mass General Brigham, with some flexibility for remote work(e.g., 1 or 2 days per week) depending on operational needs.
• Competitivecompensation and benefitspackage.