Assistant Project Scientist- Carvajal-Carmona Lab

NATURE AND PURPOSE

The Assistant Project Scientist (APS) makes significant and creative contributions to a research or creative project within his/her academic discipline. The appointee possesses the subject matter expertise and the creative energy necessary to operate at a high level of competence. The appointee will engage in activities to increase, enhance, or upgrade his/her competency. Appointees with Project (e.g., Scientist) titles may participate in university and public service. Although the APS is expected to work independently under the general guidance of an academic member with an independent research program (i.e., Professor, Professional Researcher, Specialist in Cooperative Extension, etc.), he/she is not required to develop an independent research program or reputation. Instead, he/she will carry out research or creative programs under the supervision of an individual in an academic role that automatically confers Principal Investigator status. The APS typically does not serve as a Principal Investigator but may do so in exceptional circumstances.

MAJOR RESPONSIBILITIES

RESEARCH (90%)

The Assistant Project Scientist (APS), collaborating with faculty member Luis Carvajal-Carmona (LCC), will participate in the design, preparation, and execution of wet lab experiments, as well as analyze data and draft or revise manuscripts and grant applications. The APS will lead and engage in research studies on genetic susceptibility to diseases, functional genomics, pre-clinical research, and community-participatory research, with a focus on cancer. Additionally, the APS will conduct analyses in cancer germline, somatic genetics, functional genomics, and epidemiology.

The APS will create and implement genome engineering and bioinformatics tools for generating and analyzing isogenic cell lines. This includes planning, executing, and analyzing drug efficacy assays in cancer cell lines, patient-derived organoid cultures, and xenografts. The APS will also develop cellular assays from CRISPR-Cas9 (such as CRISPR screens) or other molecular perturbagens like RNAi, small molecules, and cDNAs. Additionally, the APS will perform bioinformatics and statistical analyses of functional and genomic data, as well as functional analyses of disease-linked variants. The APS will also interact with other members of the LCC laboratory and with collaborators on various projects. The candidate will prepare drafts of all manuscripts related to their research project(s) and is expected to help mentor and train undergraduate and graduate students and other members of the LCC laboratory, including instruction on the use and development of functional genomics projects. The candidate is expected to maintain and troubleshoot protocols and processes in the lab and support laboratory management. The candidate will perform management and leadership tasks, including, but not limited to, ordering and installing wet lab-related instruments, providing technical assistance when needed, ordering supplies, and processing invoices.

PROFESSIONAL COMPETENCE AND ACTIVITY (5%)

The APS will engage in professional societies and conferences relevant to their specific field. The APS will attend seminars to present research findings and may give oral presentations to both public and professional interest groups. The APS may also coordinate and/or deliver presentations at seminars, laboratory meetings, or educational events.

UNIVERSITY AND PUBLIC SERVICE (5%)

The APS will conduct public outreach activities that involve presenting scientific research results to the general public. The APS may participate in university service activities such as guest lecturing, committee service, and voting on peer committees.

1. Candidates should have a PhD in genetics, genomics, bioinformatics or a related field.
2. A minimum of six years of post-doctoral research experience in cancer genetics.
3. Extensive functional genomics or related field knowledge is demonstrated through education, work experience, or equivalent experience.

• 3 required (contact information only)

As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct, are currently being investigated for misconduct, left a position during an investigation for alleged misconduct, or have filed an appeal with a previous employer.

• "Misconduct" means any violation of the policies or laws governing conduct at the applicant's previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment, discrimination, dishonesty, or unethical conduct, as defined by the employer.
• UC Sexual Violence and Sexual Harassment Policy
• UC Anti-Discrimination Policy for Employees, Students and Third Parties
• APM - 035: Affirmative Action and Nondiscrimination in Employment

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The University of California is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected status under state for federal law.

Under Federal law, the University of California may employ only individuals who are legally able to work in the United States as established by providing documents as specified in the Immigration Reform and Control Act of 1986. Certain UC Davis positions funded by federal contracts or sub-contracts require the selected candidate to pass an E-Verify check. More information is available at: http://www.uscis.gov/e-verify

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