Research Associate

Job Summary:

This position will focus on understanding the molecular mechanism of pre-mRNA splicing and its role in disease processes. Candidates will be expected to plan and execute independent experiments, write and publish experimental results, help with lab daily operation, contribute to grant writing, and contribute positively towards the atmosphere and culture of the lab.

Key Responsibilities:

• Design and implement molecular biology, biochemical, cell biology, and structural experiments to understand the mechanism of pre-mRNA splicing, the structure and function of spliceosome and its components, and how to modulate splicing in disease process using small molecules.
• Prepare manuscript for publication.
• Present scientific at various seminars and meetings.
• Help with lab daily operation such as supply ordering.
• Contribute to grant writing.

Work Location:

Onsite - this role is expected to work onsite and is located in Aurora, Colorado.

Why Join Us:

Our department conducts research across a wide biological scale for fundamental scientific understanding with applications to many disease contexts. The overarching goal is to reach a level of molecular insight that helps develop therapeutic approaches to disease.

As biochemists and molecular geneticists, we are amid an unprecedented time of discovery - our conception of the molecular biology of cells is going from the equivalent of grainy black-and-white to high-resolution technicolor. From deciphering the choreography of transcription complexes, chromosomes, and RNA molecules within cells to developing novel approaches to 3D molecular structure determination to understanding how viruses hijack a cell's machinery and alter its metabolome, the researchers in Biochemistry and Molecular Genetics (BMG) are at the forefronts of their fields both conceptually and technologically.

Why work for the University?

We have AMAZING benefits and offer exceptional amounts of holiday, vacation and sick leave! The University of Colorado offers an excellent benefits package including:

• Medical: Multiple plan options
• Dental: Multiple plan options
• Additional Insurance: Disability, Life, Vision
• Retirement 401(a) Plan: Employer contributes 10% of your gross pay
• Paid Time Off: Accruals over the year
• Vacation Days: 22/year (maximum accrual 352 hours)
• Sick Days: 15/year (unlimited maximum accrual)
• Holiday Days: 10/year
• Tuition Benefit: Employees have access to this benefit on all CU campuses
• ECO Pass: Reduced rate RTD Bus and light rail service

There are many additional perks & programs with the CU Advantage.

Diversity and Equity:

The University of Colorado Anschutz Medical Campus is committed to recruiting and supporting a diverse student body, faculty and administrative staff. The university strives to promote a culture of inclusiveness, respect, communication and understanding. We encourage applications from women, ethnic minorities, persons with disabilities, persons within the LGBTQ+ community and all veterans. In addition, the Anschutz Campus has also been recognized as an Age-Friendly University. The University of Colorado is committed to diversity and equality in education and employment.

Qualifications:

Minimum Requirements

Applicants must meet minimum qualifications at the time of hire.

• PhD in biology-related field
• Strong record of productivity as evidenced by peer-reviewed publications in internationally recognized journals
• Experience in structural biology, molecular biology, cell culture, and biochemical techniques

Knowledge, Skills and Abilities:

• Knowledgeable in molecular biology, biochemistry, structural biology, and cell biology
• Prior research experience in RNA biology especially pre-mRNA splicing or structural biology especially cryo-EM is highly desired
• Highly motivated, have ample scientific curiosity, have strong interpersonal skills, and be able to contribute in a positive manner to the collegial atmosphere of the laboratory and the department
• Be able to conduct independent research, and mentor more junior lab members
• Excellent communication skills

How to Apply:

For full consideration, please submit the following document(s):

1. A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position

2. Curriculum vitae / Resume

3. Five professional references including name, address, phone number (mobile number if appropriate), and email address

Applications are accepted electronically ONLY at www.cu.edu/cu-careers.

Questions should be directed to: Rui Zhao, Rui.zhao@cuanschutz.edu

Screening of Applications Begins:

Immediately and continues until March 3, 2025.

Anticipated Pay Range:

The starting salary range (or hiring range) for this position has been established as HIRING RANGE:

$66,000

The above salary range (or hiring range) represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting. This position is not eligible for overtime compensation unless it is non-exempt.

Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.

Total Compensation Calculator: http://www.cu.edu/node/153125

ADA Statement:

The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act, please contact the Human Resources ADA Coordinator at hr.adacoordinator@ucdenver.edu.

Background Check Statement:

The University of Colorado Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees.

Vaccination Statement:

CU Anschutz strongly encourages vaccination against the COVID-19 virus and other vaccine preventable diseases. If you work, visit, or volunteer in healthcare facilities or clinics operated by our affiliated hospital or clinical partners or by CU Anschutz, you will be required to comply with the vaccination and medical surveillance policies of the facilities or clinics where you work, visit, or volunteer, respectively. In addition, if you work in certain research areas or perform certain safety sensitive job duties, you must enroll in the occupational health medical surveillance program.