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NGS Research Technologist

Massachusetts General Hospital
United States, Massachusetts, Cambridge
38 Sidney Street (Show on map)
Jan 16, 2025
Research Technologist to join our Next-Generation Sequencing team. The candidate will assist with our various NGS services (Complete Plasmid Sequencing, Complete Amplicon Sequencing, CRISPR Amplicon Sequencing, Viral Genome Sequencing and 16S Sequencing) utilizing the Illumina MiSeq platform. The candidate will also assist in the continued development and daily operation of our Oxford Nanopore-based Rapid Plasmid Sequencing service. The Research Technologist reports to the Core Director and the NGS manager and is expected to work very independently. Ability to work in a collaborative and fast-paced team environment, and to interact with researchers using our services is required.

  • May develop modifications of existing assay techniques, experimental protocols, or new procedures
  • Synthesizes and interprets results
  • Prepares written and/or verbal status reports
  • Uses statistical and graphic summaries
  • Orients and trains new Research Technicians
  • Executes protocols of non-routine experiments
  • Creates new protocols for novel applications and assays
  • Designs experiments independently
  • Assists Investigator with determining the most suitable methodology
  • Performs basic design and modification of protocols
  • Performs molecular biology-based experiments
  • Maintains various electronic inventory databases
  • Makes full use of an electronic project management tool to track and bill tasks
  • Prepares lab reagents, chemicals
  • Operates lab instruments, equipment
  • Writes and implements standard operation procedures (SOPs)
  • For specific research services, works as a liaison between core laboratory and customers
  • Performs independent literature searches
  • Organizes and presents findings at lab meetings and/or to clients
  • Maintains and orders supplies
  • Assists with organizing materials for publication or presentation

SKILLS/ABILITIES/COMPETENCIES REQUIRED:

  • Ability to work independently and as a team member
  • Ability to display initiative to introduce innovation to research studies
  • Analytical skills and ability to resolve technical problems
  • Ability to interpret data
  • Ability to prioritize tasks and set deadlines
  • Superior organization skills
  • Molecular biology techniques such as DNA extraction, PCR, qPCR, and gel electrophoresis
  • Next-Generation Sequencing using Illumina instruments such as MiSeq
  • Excellent communication skills
  • Functions with speed, precision, and an understanding of theory behind tests/procedures

Education

  • Bachelor's Degree or Master's Degree in Biology or similar field

Can this role accept experience in lieu of a degree?
Yes

Licenses and Credentials

Experience

  • Minimum 3 years of directly related work experience required
  • Molecular biology experience preferred
  • Minimum 6 months experience with Next-Generation Sequencing preferred

Knowledge, Skills and Abilities
- Excellent communication skills.
- Good interpersonal skills and the ability to oversee the work of others.
- Ability to work independently.
- Ability to identify problems and develop solutions.
- Ability to prioritize tasks and set deadlines.
- Strong database management and overall computer skills.
- Functions with speed, precision and an understanding of theory behind tests and procedures.



The General Hospital Corporation is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.
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