Downstream Purification Scientist

Ecolab is seeking a Downstream Purification Scientist to develop chromatography processes and to advance technical platforms satisfying both business and customer needs. In this role you will be responsible for performing and leading chromatography experiments for industrial purification of monoclonal antibodies. You will work closely with field and lab based technical teams to design, execute and communicate results from process development studies experiments. We are seeking candidates who have strong collaboration and teamwork skills, are self-motivated, have good communication skills, are creative problem solvers, and possess strong observation and perception skills.

What's in it For You:

• The opportunity to take on some of the world's most meaningful challenges, accelerating biologic drug development processes
• The ability to make an impact and shape your career with a company that is passionate about growth
• The support of an organization that believes it is vital to include and engage diverse people, perspectives and ideas to achieve our best

What You Will Do:

• Provide technical support by demonstrating strong theoretical and fundamental knowledge, in addition to practical application, specifically chromatography, and downstream unit operations, in general.
• Routinely author protocols and reports for process development studies for purification of monoclonal antibodies.
• Design, establish and execute bench-scale applications experiments using AKTA and other bench-scale chromatography system.
• Perform process screening and optimization experiments using a Tecan high-throughput system.
• Analyze samples using HPLC, SDS-PAGE, ELISA, PCR, spectrophotometry and other appropriate analytical tools to determine product purity and non-product related impurity profile.
• Develop a robust packing protocol from small-scale to production-scale chromatography columns, including P/F characterization.
• Maintaining accurate records and interpreting data to provide detailed information and analysis on the execution of experiments
• Solid critical thinking skills with the ability to communicate technical issues, resolve complex problems and propose efficient and robust solutions.
• Follow all procedures established in the lab to ensure efficiency and safety.
• Must be able to lift up to 15 pounds at times.

Minimum Qualifications:

• BS required, MS or PhD in Biochemistry, Chemical Engineering, Biotechnology, Biology, Chemistry or related degree preferred.
• Minimum 3 years of proven chromatography and direct development experience in Process Development (PD) or MSAT.
• Demonstrated strong theoretical and fundamental knowledge of chromatography
• Demonstrated hands-on experience working with industrial purification process development of monoclonal antibodies
• The ability to exhibit a high level of attention to detail and a quality-minded approach to all record keeping
• Fully on-site position

Preferred Qualifications:

• Strong problem-solving skills
• Strong oral and written communication skills
• Understanding of fundamental physical/chemical properties and structural activity relationships
• Working knowledge of statistics

Benefits

Ecolab strives to provide comprehensive and market-competitive benefits to meet the needs of our associates and their families.Click here to see our benefits.

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