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Principal Scientist- Pathology

Genentech
United States, California, South San Francisco
Nov 20, 2024
The Position

We advance science so that we all have more time with the people we love

The successful Translational Safety Principal Pathologist candidate will provide scientific leadership and play an active role in the process of drug development from target assessment through marketed products. Working in a team environment, Translational Safety Project Pathologists participate in and may lead the strategic design, implementation, and data analysis of non-GLP investigative and GLP regulatory studies to ensure the comprehensive, highly integrated safety profiling of Genentech drug candidates.

The Opportunity:

As an integral member of this dynamic team, you will be:

  • Providing veterinary clinical, technical, and scientific expertise on in-house and CRO based studies from protocol development through necropsy, clinical pathology, and histopathology evaluations,pathology peer review and final report generation.

  • Collaborating closely with toxicologists and study operations professionals to develop expertise in the development of streamlined, innovative safety assessment programs for Genentech drug candidates, and in authoring regulatory documents.

  • Working independently to leverage literature to develop and optimize best-evidence arguments in support of data interpretation or experimental approaches.

  • Influencing Toxicologic Pathology and Industry standards via the publication of high quality scientific manuscripts.

  • Collaborating with in vitro systems scientists to characterize and qualify assays for assessment of toxicity

  • Designing and conducting in vitro and/or in vivo investigative and mechanistic studies in collaboration with toxicologists and subject matter experts

  • Participating and often lead safety biomarker and diagnostic development programs.

  • Advancing applications of digital pathology for greater scientific insights and workflow efficiencies.

  • Participating in the Immunology and Infectious Disease Expert Working Group

  • Participate in and lead interdisciplinary project teams.

  • Gain experience to represent Genentech/Roche in meetings with regulatory authorities as needed.

  • Providing functional area mentorship and leadership in Pathology

  • Performing managerial, administrative, tactical, or strategic roles within Translational Safety, Development Sciences, or gRED, commensurate with experience.

Who You Are:

  • A DVM/VMD or equivalent and board certification in the American College of Veterinary Pathology or European College of Veterinary Pathology.

  • PhD in Integrative Pathobiology, or related discipline, preferred. Alternatively, a minimum of 5 years of relevant industry experience

Preferred:

  • Experience/ interest in the development of digital pathology algorithms

  • Experience/ interest in the pathobiology of infectious diseases or inflammatory diseases of the gut and lung

Relocation benefits are available for this job posting.

The expected salary range for this position based on the primary location of South San Francisco, California is $184,700-$343,100. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status.

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