Research Scholar--McCarthy Lab

North Carolina State University

$80,000 (Commensurate education and experience)

United States, North Carolina, Raleigh

Nov 20, 2024

Posting Information

Posting Number	PG193807EP
Internal Recruitment	No
Working Title	Research Scholar--McCarthy Lab
Anticipated Hiring Range	$80,000 (Commensurate education and experience)
Work Schedule	Monday-Friday 8am-5pm
Job Location	Raleigh, NC
Department	Department of Molecular Biomedical Sciences
About the Department	North Carolina State University's College of Veterinary Medicine (NC State CVM) is a dynamic community whose members are dedicated to preparing veterinarians, veterinarian scientists, and biomedical scientists while advancing animal and human health from the cellular level through entire ecosystems. The Department of Molecular Biomedical Sciences at the NC State CVM trains veterinarians, graduate students, and postdoctoral fellows in research-based careers focused on discovering new information about animal and human health and disease and using those findings to enhance animal and human health and wellbeing.
Essential Job Duties	The McCarthy lab explores how mesenchymal cells promote proper intestinal stem cell homeostasis in development, health, and disease. We focus on how extracellular signaling pathways direct tissue/cell interactions and explore mesenchymal dysfunction in inflammatory bowel disease. Our lab uses mouse as its primary model system, including in vivo genetic techniques to characterize and assess mechanistic functions of cells in intestinal tissue homeostasis, disease, and development; epithelial perturbation via irradiation and colitis formation; and in vitro methods, primarily intestinal organoids and primary cell cultures, to test mesenchymal-epithelial functions in vitro. Their group has strong connections with gastrointestinal researchers at UNC Chapel Hill and Duke University through the NIH funded Center for Gastrointestinal Biology and Disease ( CGIBD). Primary duties include but are not limited to: Oversee and provide support with molecular biology and histology techniques with mouse and human cells as well as with mouse and human tissues. Oversee and provide support in managing mouse colonies for the lab including basic husbandry tasks, genotyping, and collection of tissue for downstream analyses. Oversee and provide support with cell culture including pluripotent stem cells, primary cells, 3D organoid cultures, and established cell lines from mouse, rat, or human origin. Oversee and record completed and accurate laboratory methods and results in an online laboratory notebook. Use appropriate tools and software to document and analyze collected data. Communicate summaries of experimental results to the lab staff and principal investigator. Assist with the evaluation, interpretation and assessment of experimental data and quality control of assays. Participate in meetings with principal investigator and research staff. Oversee ordering and maintaining supply of inventories. Oversee and operate, calibrate, and perform routine maintenance on specialized equipment used in research. Supervise and train laboratory personnel including students.
Other Responsibilities	Other duties as assigned.

Qualifications

Minimum Education and Experience	Relevant Ph.D degree (or relevant terminal degree), or relevant Master's degree with at least 5 years of formal post-degree professional work experience. In rare instances, an individual with comparable professional experience but less than a master's degree, plus 8 years of exceptional relevant professional experience. May require terminal degree and licensure.
Other Required Qualifications	Possess strong verbal, interpersonal, and organizational skills. Excellent writing skills and ability to summarize complex content and redevelop as required for the intended audience Ability to multitask and work independently with a high level of initiative Extensive technical and analytical skills in biomedical research including molecular and cellular biology Track record of collaboration, productivity, and accomplishment in a team environment Motivated, organized, with meticulous attention to detail Demonstrated record of research competency in the form of publications, presentations, and preparation of funded grant proposals Experienced in training and guiding research personnel
Preferred Qualifications	Experience working with rodents preferred Experience molecular and cellular biology assays including RNA sequencing, single-cell RNA sequencing Experience with bioinformatics would be beneficial. Experience in cell culture preferred, especially with human pluripotent stem cells Experience with microscopy preferred. Experience with genome editing techniques including CRIPSRs would be beneficial.
Required License(s) or Certification(s)	NA
Valid NC Driver's License required	No
Commercial Driver's License required	No

Recruitment Dates and Special Instructions

Job Open Date	11/19/2024
Anticipated Close Date	Open until filled
Special Instructions to Applicants	Please include as attachments a resume and the contact information for at least three professional references.

Position Details

Position Number	00111178
Position Type	EHRA Non-Faculty
Full Time Equivalent (FTE) (1.0 = 40 hours/week)	1.0
Appointment	12 Month Recurring
Mandatory Designation - Adverse Weather	Non Mandatory - Adverse Weather
Mandatory Designation - Emergency Events	Non Mandatory - Emergency Event
Department ID	194001 - Department of Molecular Biomedical Sciences
AA/EEO	NC State University is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, national origin, religion, sex, gender identity, age, sexual orientation, genetic information, status as an individual with a disability, or status as a protected veteran. Individuals with disabilities requiring disability-related accommodations in the application and interview process are welcome to contact 919-515-3148 to speak with a representative at the Office of Equal Opportunity. If you have general questions about the application process, you may contact Human Resources at (919) 515-2135 or workatncstate@ncsu.edu. Final candidates are subject to criminal & sex offender background checks. Some vacancies also require credit or motor vehicle checks. Degree(s) must be obtained prior to start date in order to meet qualifications and receive credit. NC State University participates in E-Verify. Federal law requires all employers to verify the identity and employment eligibility of all persons hired to work in the United States.