Biostatistician
Division of Pulmonary and Critical Care Medicine - ZSFG Job Summary The Biostatistician will be providing statistical support for ongoing clinical research projects, working on statistical methodological projects, and performing data analysis from multi-center randomized controlled trials, working closely with the PI, Dr. Phillips (https://profiles.ucsf.edu/patrick.phillips). The Biostatistician will primarily be responsible for supporting statistical activities that are part of the UNITE4TB consortium - a public-private partnership conducting phase II trials of new regimens for the treatment of tuberculosis (https://www.unite4tb.org/). The Biostatistician will also collaborate with other faculty in the UCSF Center for Tuberculosis.
Responsibilities of the Biostatistician include drafting sections for trial protocols pertaining to statistics, providing statistical support for data capture forms (case report forms, CRFs) and database specifications for the trials, drafting the statistical analysis plan, contributing to study standard operating procedures (SOPs), responding to queries from collaborators on statistical issues, joining team and project meetings, writing code for data analysis, performing interim data analyses for reporting to Data Safety and Monitoring Boards (DSMBs), providing regular reports for reports to funders and other stakeholders, and performing final analyses at trial completion. In all these activities, the Biostatistician will work closely with Dr. Phillips.
The Biostatistician will join an existing team of Masters-level and PhD-level Biostatisticians within the UCSF Center for TB Biostatistics Core working on tuberculosis clinical research projects, led by Dr. Phillips (https://tb.ucsf.edu/biostatistics-core). The Biostatistician will have the opportunity to attend biostatistics webinars (and other training activities) organized by the Department of Epidemiology and Biostatistics.
The Biostatistician will be part of multi-disciplinary project teams involving study coordinators, clinicians, data managers, pharmacists, and others both within UCSF and at collaborating institutions in the US and globally. Most studies are based internationally with collaborators in the US as well as in Europe, Africa, and East Asia.
The Biostatistician may be required to undertake domestic or international travel for study site visits and conference attendance, depending on job requirements and grant funding availability.
The Biostatistician will also have the opportunity to undertake statistical methodological work. The focus of the methodology will be to address specific aspects in the ongoing projects, particularly clinical trials to improve the diagnosis and treatment of tuberculosis, the world's deadliest infectious disease.
The post-holder will initially receive close support and supervision while increasingly taking responsibility for organizing and managing their own workload independently. Mentoring for career development will be provided by Dr. Phillips. The post holder will contribute to publications and grant applications (for both clinical and statistical projects). They will have an opportunity to write their own first-author publications or contribute to publications as an author based on their own work or collaborative work within their projects.
The post holder is expected to develop their knowledge of the biology and epidemiology of relevant disease areas by reading relevant journals, attending journal clubs, conferences, etc.
The post holder may undertake the work fully or partly remote with some flexibility in working hours, although the UCSF Center for TB Biostatistics Core strongly advocates an appropriate work-life balance. The post-holder must be located within the US.
***Note: This is a hybrid role with occasional needs for calls in non-work hours. The final salary and offer components are subject to additional approvals based on UC policy. Your placement within the salary range is dependent on a number of factors including your work experience and internal equity within this position classification at UCSF. For positions that are represented by a labor union, placement within the salary range will be guided by the rules in the collective bargaining agreement. The salary range for this position is $84,400 - $120,100 (Annual Rate). To learn more about the benefits of working at UCSF, including total compensation, please visit: https://ucnet.universityofcalifornia.edu/compensation-and-benefits/index.html Department Description The mission of the Division of Pulmonary and Critical Care Medicine at ZSFG is to provide comprehensive medical care for the community, to develop innovative research aimed at elucidating basic mechanisms of disease, and to translate its research activities into both new clinical initiatives and a rich training environment for the next generation of academic physician scientists.
Dr. Phillips (https://profiles.ucsf.edu/patrick.phillips) has joint appointments in the Department of Medicine and the Department of Epidemiology and Biostatistics at UCSF and leads the UCSF Center for Tuberculosis Biostatistics Core. The objective of Dr. Phillips' research is to design, implement, and optimize clinical trials for new treatments for tuberculosis in order to deliver safer and more efficacious regimens for patients. He is lead statistician for several international tuberculosis trials networks and has been primary senior statistician for a number of high impact phase II and phase III tuberculosis clinical trials. He leads a team of masters-level and PhD-level statisticians providing statistical support to many ongoing TB trials and working on applied clinical trials methodology. Required Qualifications
- Bachelor's degree in Statistics/Biostatistics or related area and three or more years of relevant experience and / or equivalent experience/training.
- Human Subjects Research training or ability to obtain in the first year of employment.
- At least 1 year of practical work experience in clinical trials or related work.
- Knowledge of statistical programs including R or Stata (R strongly preferred)..
- Thorough knowledge of research function.
- Thorough skills associated with statistical analysis and statistical methodology.
- Thorough understanding of statistical aspects of randomized clinical trials.
- Skills to communicate complex information in a clear and concise manner both verbally and in writing.
- Contributions to peer-reviewed publications in scientific journals and/or grant applications.
- Ability to take on responsibility for the day-to-day management of statistical aspects of a project.
- Ability to work effectively in a multi-disciplinary team.
- Attention to detail.
Preferred Qualifications
- PhD in Biostatistics (or a closely related subject).
- Experience working in or with the pharmaceutical industry, or in clinical research conducted under the auspices of a stringent regulatory authority.
- Familiarity with standards for clinical trials including ICH GCP, FDA or EMA requirements, CONSORT, SPIRIT, etc.
- Research skills at a level to evaluate alternate solutions and develop recommendations.
- Knowledge of medical terminology with a focus on tuberculosis.
- Experience with Quarto and/or R Markdown for reproducible reporting of statistical analyses.
About UCSF The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences. We bring together the world's leading experts in nearly every area of health. We are home to five Nobel laureates who have advanced the understanding of cancer, neurodegenerative diseases, aging and stem cells. Pride Values UCSF is a diverse community made of people with many skills and talents. We seek candidates whose work experience or community service has prepared them to contribute to our commitment to professionalism, respect, integrity, diversity and excellence - also known as our PRIDE values.
In addition to our PRIDE values, UCSF is committed to equity - both in how we deliver care as well as our workforce. We are committed to building a broadly diverse community, nurturing a culture that is welcoming and supportive, and engaging diverse ideas for the provision of culturally competent education, discovery, and patient care. Additional information about UCSF is available at diversity.ucsf.edu
Join us to find a rewarding career contributing to improving healthcare worldwide. Equal Employment Opportunity The University of California San Francisco is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information. Job Code and Payroll Title 006257 RSCH DATA ANL 3 Job Category Professional (Non-Clinical), Research and Scientific Bargaining Unit 99 - Policy-Covered (No Bargaining Unit) Location San Francisco, CA Campus Zuckerberg San Francisco General (ZSFG) Additional Shift Details Monday - Friday, 40 hours/week, 800 am - 5:00 pm with occasional needs for calls in non-work hours |
University of California - San Francisco Campus and Health
Nov 23, 2024